Issue 38, 2012
From the journal:

Chemical Communications

Hemin/G-quadruplex simultaneously acts as NADH oxidase and HRP-mimicking DNAzyme for simple, sensitive pseudobienzyme electrochemical detection of thrombin†

Yali Yuan,a   Ruo Yuan,*a   Yaqin Chai,a   Ying Zhuo,a   Xiaoya Ye,a   Xianxue Gana  and  Lijuan Baia  

* Corresponding authors

a Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China
E-mail: yuanruo@swu.edu.cn
Fax: +86-23-68252277
Tel: +86-23-68252277

Abstract

For the first time, hemin/G-quadruplex was employed to simultaneously serve as NADH oxidase and an HRP-mimicking DNAzyme for constructing a simple and sensitive pseudobienzyme-amplifying electrochemical aptasensor for thrombin detection.

Graphical abstract: Hemin/G-quadruplex simultaneously acts as NADH oxidase and HRP-mimicking DNAzyme for simple, sensitive pseudobienzyme electrochemical detection of thrombin

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Article information

DOI
https://doi.org/10.1039/C2CC31423A
Article type
Communication
Submitted
27 Feb 2012
Accepted
07 Mar 2012
First published
08 Mar 2012

Chem. Commun., 2012,48, 4621-4623

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Hemin/G-quadruplex simultaneously acts as NADH oxidase and HRP-mimicking DNAzyme for simple, sensitive pseudobienzyme electrochemical detection of thrombin

Y. Yuan, R. Yuan, Y. Chai, Y. Zhuo, X. Ye, X. Gan and L. Bai, Chem. Commun., 2012, 48, 4621 DOI: 10.1039/C2CC31423A

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