Issue 43, 2012
From the journal:

Chemical Communications

A turn-on fluorescent probe based on hydroxylamineoxidation for detecting ferric ion selectively in living cells†

Rui Wang,a   Fabiao Yu,b   Ping Liua  and  Lingxin Chen*a  

* Corresponding authors

a Key Laboratory of Coastal Zone Environmental Processes, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, P. R. China
E-mail: lxchen@yic.ac.cn
Fax: (+86) 535-2109130
Tel: (+86) 535-2109130

b School of Chemical Engineering, Dalian University of Technology, Dalian 116024, P. R. China
E-mail: yufabiao@163.com

Abstract

We have described a turn on fluorescent probe BOD-NHOH based on hydroxylamine oxidation for detecting intracellular ferric ions. The probe comprises a signal transducer of BODIPY dye and a Fe3+-response modulator of hydroxylamine. It is readily employed for assessing intracellular ferric ion levels, and confocal imaging is achieved successfully.

Graphical abstract: A turn-on fluorescent probe based on hydroxylamine oxidation for detecting ferric ion selectively in living cells

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Article information

DOI
https://doi.org/10.1039/C2CC31426F
Article type
Communication
Submitted
27 Feb 2012
Accepted
22 Mar 2012
First published
23 Mar 2012

Chem. Commun., 2012,48, 5310-5312

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A turn-on fluorescent probe based on hydroxylamine oxidation for detecting ferric ion selectively in living cells

R. Wang, F. Yu, P. Liu and L. Chen, Chem. Commun., 2012, 48, 5310 DOI: 10.1039/C2CC31426F

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