Issue 43, 2012
From the journal:

Chemical Communications

The role of lipophilicity in transmembrane anion transport†

Vittorio Saggiomo,a   Sijbren Otto,a   Igor Marques,b   Vítor Félix,b   Tomás Torrobac  and  Roberto Quesada*c  

* Corresponding authors

a Centre for Systems Chemistry, Stratingh Institute, University of Groningen, 9747 AG Groningen, The Netherlands

b Departamento de Química, CICECO and Secção Autónoma de Ciências da Saúde, Universidade de Aveiro, 3810-193 Aveiro, Portugal

c Departamento de Química, Facultad de Ciencias, Universidad de Burgos, 09001 Burgos, Spain
E-mail: rquesada@ubu.es

Abstract

The transmembrane anion transport activity of a series of synthetic molecules inspired by the structure of tambjamine alkaloids can be tuned by varying the lipophilicity of the receptor, with carriers within a certain log P range performing best.

Graphical abstract: The role of lipophilicity in transmembrane anion transport

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Article information

DOI
https://doi.org/10.1039/C2CC31825C
Article type
Communication
Submitted
12 Mar 2012
Accepted
10 Apr 2012
First published
24 Apr 2012

Chem. Commun., 2012,48, 5274-5276

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The role of lipophilicity in transmembrane anion transport

V. Saggiomo, S. Otto, I. Marques, V. Félix, T. Torroba and R. Quesada, Chem. Commun., 2012, 48, 5274 DOI: 10.1039/C2CC31825C

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