We describe a signal amplified biosensor based on self-assembled optical diffraction grating of a Fresnel zone plate structure. Diffracted light rays passed through gratings are interfered constructively at the focal point, resulting in the enhanced signal amplification without sacrificing signal-to-noise ratio (SNR).
Y. Jeong, B. Jung, J. Park and J. Park, Chem. Commun., 2012, 48, 6378 DOI: 10.1039/C2CC32008H
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