Issue 53, 2012

Interaction between GUVs and catanionic nanocontainers: new insight into spontaneous membrane fusion

Abstract

Spontaneous receptor-free membrane fusion with pure lipid systems, used as a cell membrane model, is demonstrated with easy-to-handle lactose-derived catanionic vesicles. This fusion, mediated and controlled by phospholipids, emphasizes the great value of these nanovesicles for enhanced direct cytosolic drug delivery without the shortcomings linked with endocytic pathways.

Graphical abstract: Interaction between GUVs and catanionic nanocontainers: new insight into spontaneous membrane fusion

Supplementary files

Article information

Article type
Communication
Submitted
22 Mar 2012
Accepted
14 May 2012
First published
15 May 2012

Chem. Commun., 2012,48, 6648-6650

Interaction between GUVs and catanionic nanocontainers: new insight into spontaneous membrane fusion

C. Mauroy, P. Castagnos, M. Blache, J. Teissié, I. Rico-Lattes, M. Rols and M. Blanzat, Chem. Commun., 2012, 48, 6648 DOI: 10.1039/C2CC32093B

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