Issue 63, 2012

Structure–activity effects in peptideself-assembly and gelation – Dendritic versus linear architectures

Abstract

We demonstrate that linear-dendritic shape-isomerism can have an impact on the gelation potential of peptides based on lysine, but the architectural effects can be inverted depending on the choice of functional groups, with the nature of these protecting groups dominating the gelation ability.

Graphical abstract: Structure–activity effects in peptide self-assembly and gelation – Dendritic versus linear architectures

Supplementary files

Article information

Article type
Communication
Submitted
24 Apr 2012
Accepted
12 Jun 2012
First published
03 Jul 2012

Chem. Commun., 2012,48, 7817-7819

Structure–activity effects in peptide self-assembly and gelation – Dendritic versus linear architectures

C. A. Lagadec and David. K. Smith, Chem. Commun., 2012, 48, 7817 DOI: 10.1039/C2CC32921B

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