Issue 65, 2012
From the journal:

Chemical Communications

Carrier-free, functionalized drugnanoparticles for targeted drug delivery†

Wei Li,a   Yinlong Yang,a   Chao Wang,a   Zhuang Liu,a   Xiujuan Zhang,*a   Feifei An,b   Xiaojun Diao,a   Xiaojun Haoa  and  Xiaohong Zhang*b  

* Corresponding authors

a Functional Nano & Soft Materials Laboratory (FUNSOM) and Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Soochow University, Suzhou, Jiangsu, 215123, P. R. China
E-mail: xjzhang@suda.edu.cn
Fax: 86 512 65882846
Tel: 86 512 65889855

b Nano-organic Photoelectronic Laboratory and Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China
E-mail: xhzhang@mail.ipc.ac.cn
Tel: 86 10 82543510

Abstract

We demonstrate a new concept of carrier-free functionalized drug nanoparticles for targeted drug delivery. It exhibits significantly enhanced drug efficacy to folate receptor-positive cells with high selectivity and a high drug loading content up to more than 78%.

Graphical abstract: Carrier-free, functionalized drug nanoparticles for targeted drug delivery

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Article information

DOI
https://doi.org/10.1039/C2CC33214K
Article type
Communication
Submitted
04 May 2012
Accepted
21 Jun 2012
First published
21 Jun 2012

Chem. Commun., 2012,48, 8120-8122

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Carrier-free, functionalized drug nanoparticles for targeted drug delivery

W. Li, Y. Yang, C. Wang, Z. Liu, X. Zhang, F. An, X. Diao, X. Hao and X. Zhang, Chem. Commun., 2012, 48, 8120 DOI: 10.1039/C2CC33214K

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