Issue 62, 2012

DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles

Abstract

A lateral flow test strip assay, enabling sensitive detection of DNA specific to the foodborne pathogen E. coli O157:H7, is described. The use of LNA-conjugated gold nanoparticle probes, along with signal amplification protocols, results in minimum detectable concentrations of ∼0.4 nM.

Graphical abstract: DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles

Supplementary files

Article information

Article type
Communication
Submitted
11 May 2012
Accepted
11 Jun 2012
First published
13 Jun 2012

Chem. Commun., 2012,48, 7714-7716

DNA detection on lateral flow test strips: enhanced signal sensitivity using LNA-conjugated gold nanoparticles

S. K. Rastogi, C. M. Gibson, J. R. Branen, D. Eric Aston, A. Larry Branen and P. J. Hrdlicka, Chem. Commun., 2012, 48, 7714 DOI: 10.1039/C2CC33430E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements