Issue 69, 2012
From the journal:

Chemical Communications

Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants†

Jian Zhang,a   Hefang Shi,a   Yuyong Maa  and  Biao Yu*a  

* Corresponding authors

a State Key Laboratory of Bio-organic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China
E-mail: byu@mail.sioc.ac.cn
Fax: (0086)-21-64166128

Abstract

Pregnane glycoside P57, the appetite suppressant component from Hoodia, was synthesized expeditiously, featuring preparation of the aglycone Hoodigogenin A from digoxin and assembly of the deoxytrisaccharide with glycosyl o-alkynylbenzoates as donors.

Graphical abstract: Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants

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Article information

DOI
https://doi.org/10.1039/C2CC34404A
Article type
Communication
Submitted
20 Jun 2012
Accepted
06 Jul 2012
First published
06 Jul 2012

Chem. Commun., 2012,48, 8679-8681

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Expeditious synthesis of saponin P57, an appetite suppressant from Hoodia plants

J. Zhang, H. Shi, Y. Ma and B. Yu, Chem. Commun., 2012, 48, 8679 DOI: 10.1039/C2CC34404A

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