Issue 71, 2012
From the journal:

Chemical Communications

A low-molecular-weight supramolecular hydrogel of riboflavinbolaamphiphile for VEGF-siRNA delivery†‡§

Sachin Prakash Patil,a   Hyun Seok Jeonga  and  Byeang Hyean Kim*a  

* Corresponding authors

a Department of Chemistry, Division of IBB, Pohang University of Science and Technology, Pohang 790-784, Korea
E-mail: bhkim@postech.ac.kr
Fax: +82 54 279 3399
Tel: +82 54 279 2115

Abstract

A low-molecular-weight hydrogel derived from riboflavin (vitamin B2) that self-assembles to provide supramolecular nanofibers, biocompatible material, can be used to deliver VEGF-siRNA efficiently into human cells by the endocytosis pathway, where the siRNA is functionalized.

Graphical abstract: A low-molecular-weight supramolecular hydrogel of riboflavin bolaamphiphile for VEGF-siRNA delivery

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Article information

DOI
https://doi.org/10.1039/C2CC34466A
Article type
Communication
Submitted
16 Apr 2012
Accepted
20 Jul 2012
First published
20 Jul 2012

Chem. Commun., 2012,48, 8901-8903

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A low-molecular-weight supramolecular hydrogel of riboflavin bolaamphiphile for VEGF-siRNA delivery

S. P. Patil, H. S. Jeong and B. H. Kim, Chem. Commun., 2012, 48, 8901 DOI: 10.1039/C2CC34466A

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