Issue 79, 2012
From the journal:

Chemical Communications

A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines†

Zhenjun Mao,a   Haijun Qu,a   Yanyan Zhaoa  and  Xufeng Lin*a  

* Corresponding authors

a Department of Chemistry, Zhejiang University, Hangzhou 310027, China
E-mail: lxfok@zju.edu.cn

Abstract

1,1-Cyclopropane aminoketones were efficiently synthesized in high yields by the tandem reaction of α-amino aryl ketones with vinyl sulfonium salts using DBU as the base in CH2Cl2. This methodology was utilized to synthesize 2-benzoyl quinolines.

Graphical abstract: A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines

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Article information

DOI
https://doi.org/10.1039/C2CC35235D
Article type
Communication
Submitted
20 Jul 2012
Accepted
18 Aug 2012
First published
20 Aug 2012

Chem. Commun., 2012,48, 9927-9929

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A general access to 1,1-cyclopropane aminoketones and their conversion into 2-benzoyl quinolines

Z. Mao, H. Qu, Y. Zhao and X. Lin, Chem. Commun., 2012, 48, 9927 DOI: 10.1039/C2CC35235D

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