Issue 81, 2012

nBu4NI-catalyzed direct synthesis of α-ketoamides from aryl methyl ketones with dialkylformamides in water using TBHP as oxidant

Abstract

A novel and easy practical direct synthesis of α-ketoamides has been developed without metals in water. This procedure was catalyzed by nBu4NI using TBHP as oxidant from simple substrates, aryl methyl ketones and dialkylformamides.

Graphical abstract: nBu4NI-catalyzed direct synthesis of α-ketoamides from aryl methyl ketones with dialkylformamides in water using TBHP as oxidant

Supplementary files

Article information

Article type
Communication
Submitted
22 Jul 2012
Accepted
22 Aug 2012
First published
23 Aug 2012

Chem. Commun., 2012,48, 10117-10119

nBu4NI-catalyzed direct synthesis of α-ketoamides from aryl methyl ketones with dialkylformamides in water using TBHP as oxidant

W. Mai, H. Wang, Z. Li, J. Yuan, Y. Xiao, L. Yang, P. Mao and L. Qu, Chem. Commun., 2012, 48, 10117 DOI: 10.1039/C2CC35279F

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