Issue 94, 2012
From the journal:

Chemical Communications

Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth†

Sen Wang,‡a   Xin Wen,*b   Pavle Nikolovski,c   Vonny Juwitab  and  Josh Fnu Arifinb  

* Corresponding authors

a Molecular Imaging Program, Stanford University, Stanford, USA
E-mail: swang02@stanford.edu

b Department of Chemistry and Biochemistry, California State University Los Angeles, Los Angeles, USA
E-mail: xwen3@calstatela.edu
Fax: +1 323 343 6490
Tel: +1 323 343 2310

c Molecular Observatory, California Institute of Technology, Pasadena, USA

Abstract

Despite differences in the crystal structures of ice and nucleosides, antifreeze polypeptides (AFPs) have been demonstrated to inhibit nucleation of 5-methyluridine, cytidine, and inosine and modify the crystal growth of the nucleosides efficiently. The molecular recognition repertoire of AFPs has been expanded to non-ice-like crystalline solids.

Graphical abstract: Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth

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Article information

DOI
https://doi.org/10.1039/C2CC36264C
Article type
Communication
Submitted
28 Aug 2012
Accepted
15 Oct 2012
First published
15 Oct 2012

Chem. Commun., 2012,48, 11555-11557

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Expanding the molecular recognition repertoire of antifreeze polypeptides: effects on nucleoside crystal growth

S. Wang, X. Wen, P. Nikolovski, V. Juwita and J. F. Arifin, Chem. Commun., 2012, 48, 11555 DOI: 10.1039/C2CC36264C

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