Issue 11, 2012
From the journal:

Green Chemistry

Ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions†

Can Cui,a   Cong Zhu,a   Xiu-Jiang Du,a   Zhi-Peng Wang,a   Zheng-Ming Lia  and  Wei-Guang Zhao*a  

* Corresponding authors

a State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center (Tianjin), Nankai University, Tianjin 300071, China
E-mail: zwg@nankai.edu.cn
Fax: +862223505948
Tel: +862223498368

Abstract

A facile, efficient and environmentally-friendly protocol for the synthesis of α-acyloxy amides has been developed by ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions. This method provides several advantages over current reaction methodologies including a simpler work-up procedure, shorter reaction times and higher yields.

Graphical abstract: Ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions

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Article information

DOI
https://doi.org/10.1039/C2GC36095K
Article type
Paper
Submitted
15 Jul 2012
Accepted
31 Aug 2012
First published
04 Sep 2012

Green Chem., 2012,14, 3157-3163

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Ultrasound-promoted sterically congested Passerini reactions under solvent-free conditions

C. Cui, C. Zhu, X. Du, Z. Wang, Z. Li and W. Zhao, Green Chem., 2012, 14, 3157 DOI: 10.1039/C2GC36095K

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