Xueen Fang, Hui Chen, Lingjia Xu, Xingyu Jiang, Wenjuan Wu and Jilie Kong
Lab Chip, 2012,12, 1495-1499
DOI:
10.1039/C2LC40055C,
Paper
In this work, we developed a portable integrated microchip of loop-mediated isothermal nucleic acid amplification (LAMP). This chip, with sample-to-answer capability, could perform rapid DNA release, exponential signal amplification and naked-eye result read-out in single or multiplex format. We call it iμLAMP, namely integrated micro-LAMP, which was successfully used for point-of-care identification of bacteria.