Issue 13, 2012

Low frequency heating of gold nanoparticle dispersions for non-invasive thermal therapies

Abstract

Recently gold nanoparticles (GNPs) have been proposed in non-invasive thermal therapies for cancer treatment coupled with radiofrequency (RF) waves. In this work, the dissipation of RF energy by GNPs is systematically investigated both experimentally and theoretically under an EM frequency of 13.56 MHz. To elucidate the impurity effect, purified GNP dispersions are obtained through an ultrasonic-aided method. The result reveals a small bulk temperature increase, i.e., less than one centigrade for impurified samples, and even smaller for purified samples, which contrasts significantly to some earlier publications. The measured dielectric properties of GNP dispersions show a negligible change in the effective conductivities for purified samples, which indicates that the dielectric loss alone does not predict substantial temperature increase of GNPs. Further discussion shows that none of the established theories supports the idea that GNPs can dissipate RF energy significantly.

Graphical abstract: Low frequency heating of gold nanoparticle dispersions for non-invasive thermal therapies

Article information

Article type
Paper
Submitted
19 Jan 2012
Accepted
23 Apr 2012
First published
26 Apr 2012

Nanoscale, 2012,4, 3945-3953

Low frequency heating of gold nanoparticle dispersions for non-invasive thermal therapies

X. Liu, H. Chen, X. Chen, C. Parini and D. Wen, Nanoscale, 2012, 4, 3945 DOI: 10.1039/C2NR30166K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements