We report on highly selective binding of a naphthyridine derivative with a trifluoromethyl group to cytosine opposite an abasic site in DNA duplexes; the binding-induced fluorescence quenching is applicable to the analysis of a C-related single-base mutation in DNAs amplified by PCR.
Y. Sato, Y. Zhang, T. Seino, T. Sugimoto, S. Nishizawa and N. Teramae, Org. Biomol. Chem., 2012, 10, 4003 DOI: 10.1039/C2OB25513H
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