We prepared a series of new iminosugar–ferrocene hybrids displaying potent inhibition of fucosidase (bovine kidney) and inactivation of MDA-MB-231 breast cancer cells proliferation at low micromolar concentrations. The synthetic route brought to light an unprecedented isomerisation of a 2-ethanalylpyrrolidine.
A. Hottin, F. Dubar, A. Steenackers, P. Delannoy, C. Biot and J. Behr, Org. Biomol. Chem., 2012, 10, 5592 DOI: 10.1039/C2OB25727K
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