A two-step synthesis of 7,8-dichloro-riboflavin with high yield†
Abstract
We report a two-step protocol for the synthesis of 7,8-dichloro-riboflavin with a 2.5-fold increase in yield compared to previous five-step protocol methods.
* Corresponding authors
a
CNRS, CRPP, UPR 8641, Univ. Bordeaux, Pessac, France
E-mail:
mano@crpp-bordeaux.cnrs.fr
b Division of Materials Science, Faculty of Pure and Applied Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, Japan
We report a two-step protocol for the synthesis of 7,8-dichloro-riboflavin with a 2.5-fold increase in yield compared to previous five-step protocol methods.
O. Courjean, A. Hochedez, W. Neri, F. Louërat, E. Tremey, S. Gounel, S. Tsujimura and N. Mano, RSC Adv., 2012, 2, 2700 DOI: 10.1039/C2RA01211A
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