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A straightforward synthesis of pyrrolo[2,1-a]isoquinolines has been achieved from 1,3-dipolar cycloaddition reaction between isoquinoliniums and alkynes in the presence of K2CO3, and features with versatility, easy operation and mild reaction conditions. 22 examples were synthesized.

Graphical abstract: Novel syntheses of pyrrolo[2,1-a]isoquinolines via 1,3-dipolar cycloaddition between Isoquinoliniums and alkynes

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