Issue 1, 2013

A simple method for the determination of enantiomeric composition of propranolol enantiomers

Abstract

A simple method of room temperature phosphorescence is proposed for the determination of propranolol enantiomeric composition based on β-cyclodextrin as the chiral host and bromocyclohexane as the heavy atom. Enantiomeric complexes are formed upon binding of the propranolol enantiomer to β-cyclodextrin, and the sign of the resultant phosphorescence signals allows for the identity of the propranolol enantiomers configuration to be determined successfully.

Graphical abstract: A simple method for the determination of enantiomeric composition of propranolol enantiomers

Article information

Article type
Communication
Submitted
24 Jul 2012
Accepted
30 Oct 2012
First published
31 Oct 2012

Analyst, 2013,138, 107-110

A simple method for the determination of enantiomeric composition of propranolol enantiomers

Y. Wei, H. Kang, Y. Ren, G. Qin, S. Shuang and C. Dong, Analyst, 2013, 138, 107 DOI: 10.1039/C2AN36003A

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