Issue 18, 2013

Ambient pressure thermal desorption ionization mass spectrometry for the analysis of substances of forensic interest

Abstract

The large backlog of forensic samples needing chemical analysis requires new tools with high specificity, throughput, and reliability. Mass spectrometric techniques have the specificity and reliability necessary for identification, but often require sample preparation before analysis. The growth of ambient pressure ionization techniques has the capability to reduce the need for lengthy preparation. This report presents one possible technique, ambient pressure thermal desorption ionization mass spectrometry, which could prove to be useful to the forensic science community. Example mass spectra for several explosive compounds and illicit drugs obtained from liquid and bulk samples with almost no sample preparation are presented. The use of the technique for quantitative analysis is also addressed.

Graphical abstract: Ambient pressure thermal desorption ionization mass spectrometry for the analysis of substances of forensic interest

Article information

Article type
Paper
Submitted
11 Apr 2013
Accepted
11 Jul 2013
First published
12 Jul 2013

Analyst, 2013,138, 5332-5337

Ambient pressure thermal desorption ionization mass spectrometry for the analysis of substances of forensic interest

L. T. Demoranville and T. M. Brewer, Analyst, 2013, 138, 5332 DOI: 10.1039/C3AN00726J

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