Issue 8, 2013
From the journal:

Chemical Communications

Copper-catalyzed C–N bond formation through C–H/N–H activation: a novel approach to the synthesis of multisubstituted ureas†

Honglai Jiang,a   Aijun Lin,a   Chengjian Zhu*ab  and  Yixiang Chenga  

* Corresponding authors

a State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, People's Republic of China
E-mail: cjzhu@nju.edu.cn

b State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Shanghai 200032, People's Republic of China

Abstract

A copper-catalyzed cross-dehydrogenative coupling reaction that involves C–H activation of formamides and N–H activation of N-alkoxy amides has been developed. This protocol affords a novel approach to the synthesis of multisubstituted ureas under mild conditions.

Graphical abstract: Copper-catalyzed C–N bond formation through C–H/N–H activation: a novel approach to the synthesis of multisubstituted ureas

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C2CC36417D
Article type
Communication
Submitted
03 Sep 2012
Accepted
20 Nov 2012
First published
22 Nov 2012

Chem. Commun., 2013,49, 819-821

Permissions

Request permissions

Copper-catalyzed C–N bond formation through C–H/N–H activation: a novel approach to the synthesis of multisubstituted ureas

H. Jiang, A. Lin, C. Zhu and Y. Cheng, Chem. Commun., 2013, 49, 819 DOI: 10.1039/C2CC36417D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements