Issue 39, 2013
From the journal:

Chemical Communications

Cyclometalated iridium(iii) polypyridine dibenzocyclooctyne complexes as the first phosphorescent bioorthogonal probes†‡

Kenneth Kam-Wing Lo,*a   Bruce Ting-Ngok Chan,a   Hua-Wei Liu,a   Kenneth Yin Zhang,a   Steve Po-Yam Lia  and  Tommy Siu-Ming Tanga  

* Corresponding authors

a Department of Biology and Chemistry, City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, People's Republic of China
E-mail: bhkenlo@cityu.edu.hk
Fax: +852 3442 0522

Abstract

We report the synthesis, photophysical behavior, and biological properties of new cyclometalated iridium(III) polypyridine complexes appended with a dibenzocyclooctyne (DIBO) moiety; these complexes have been utilized as the first phosphorescent bioorthogonal probes for azide-modified biomolecules.

Graphical abstract: Cyclometalated iridium(iii) polypyridine dibenzocyclooctyne complexes as the first phosphorescent bioorthogonal probes

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Article information

DOI
https://doi.org/10.1039/C2CC36907A
Article type
Communication
Submitted
24 Sep 2012
Accepted
18 Oct 2012
First published
18 Oct 2012

Chem. Commun., 2013,49, 4271-4273

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Cyclometalated iridium(III) polypyridine dibenzocyclooctyne complexes as the first phosphorescent bioorthogonal probes

K. K. Lo, B. T. Chan, H. Liu, K. Y. Zhang, S. P. Li and T. S. Tang, Chem. Commun., 2013, 49, 4271 DOI: 10.1039/C2CC36907A

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