Issue 6, 2013
From the journal:

Chemical Communications

Cadmium-free quantum dots as time-gated bioimaging probes in highly-autofluorescent human breast cancer cells†

Gopa Mandal,a   Molly Darragh,b   Y. Andrew Wangb  and  Colin D. Heyes*a  

* Corresponding authors

a Department of Chemistry and Biochemistry, University of Arkansas, 345 N. Campus Drive, Fayetteville, AR, USA
E-mail: cheyes@uark.edu
Fax: +1 479-575-4049
Tel: +1 479-575-5607

b Ocean NanoTech, 2143 Worth Lane, Springdale, AR, USA

Abstract

We report cadmium-free, biocompatible (Zn)CuInS2 quantum dots with long fluorescence lifetimes as superior bioimaging probes using time-gated detection to suppress cell autofluorescence and improve the signal : background ratio by an order of magnitude. These results will be important for developing non-toxic fluorescence imaging probes for ultrasensitive biomedical diagnostics.

Graphical abstract: Cadmium-free quantum dots as time-gated bioimaging probes in highly-autofluorescent human breast cancer cells

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Article information

DOI
https://doi.org/10.1039/C2CC37529J
Article type
Communication
Submitted
16 Oct 2012
Accepted
13 Nov 2012
First published
13 Nov 2012

Chem. Commun., 2013,49, 624-626

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Cadmium-free quantum dots as time-gated bioimaging probes in highly-autofluorescent human breast cancer cells

G. Mandal, M. Darragh, Y. A. Wang and C. D. Heyes, Chem. Commun., 2013, 49, 624 DOI: 10.1039/C2CC37529J

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