Issue 8, 2013
From the journal:

Chemical Communications

A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione†‡

Ka-Ho Leung,a   Hong-Zhang He,a   Victor Pui-Yan Ma,a   Daniel Shiu-Hin Chan,a   Chung-Hang Leung*b  and  Dik-Lung Ma*a  

* Corresponding authors

a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
E-mail: edmondma@hkbu.edu.hk

b State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China
E-mail: duncanleung@umac.mo

Abstract

A G-quadruplex-selective luminescent iridium(III) switch-on probe has been developed for the detection of cysteine (Cys) in aqueous solution. The system is highly sensitive and selective towards Cys with a tunable range of detection. The detection of glutathione (GSH) is also examined.

Graphical abstract: A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione

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Article information

DOI
https://doi.org/10.1039/C2CC37710A
Article type
Communication
Submitted
29 Jul 2012
Accepted
19 Nov 2012
First published
20 Nov 2012

Chem. Commun., 2013,49, 771-773

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A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione

K. Leung, H. He, V. P. Ma, D. S. Chan, C. Leung and D. Ma, Chem. Commun., 2013, 49, 771 DOI: 10.1039/C2CC37710A

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