Issue 13, 2013
From the journal:

Chemical Communications

DNA duplex stabilization in crowded polyanion solutions†

Imran Khimji,a   Jeehae Shina  and  Juewen Liu*a  

* Corresponding authors

a Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, Canada
E-mail: liujw@uwaterloo.ca
Fax: +1 519 7460435
Tel: +1 519 8884567 Ext. 38919

Abstract

The melting temperature of duplex DNA is much higher in polyanions than in non-ionic polymers with similar ionic strength, suggesting an additional electrostatic contribution on top of the excluded volume effect.

Graphical abstract: DNA duplex stabilization in crowded polyanion solutions

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Article information

DOI
https://doi.org/10.1039/C2CC38627E
Article type
Communication
Submitted
02 Nov 2012
Accepted
21 Dec 2012
First published
21 Dec 2012

Chem. Commun., 2013,49, 1306-1308

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DNA duplex stabilization in crowded polyanion solutions

I. Khimji, J. Shin and J. Liu, Chem. Commun., 2013, 49, 1306 DOI: 10.1039/C2CC38627E

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