Issue 18, 2013
From the journal:

Chemical Communications

A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells†

Ting Guo,a   Lei Cui,a   Jiaoning Shen,a   Rui Wang,a   Weiping Zhu,a   Yufang Xu*a  and  Xuhong Qian*a  

* Corresponding authors

a State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai, China
E-mail: xhqian@ecsut.edu.cn, yfxu@ecust.edu.cn
Fax: +86-21-64252603

Abstract

A novel dual-emission fluorescence probe has been developed for specific and sensitive detection of hypochlorite (ClO−). Upon addition of ClO−, significant changes in fluorescence emission intensity at two discrete wavelengths were observed. Meanwhile OONO− led to only a single-channel fluorescence enhancement. This feature makes it a clear advantage in distinguishing ClO−, RNS from other ROS.

Graphical abstract: A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

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Article information

DOI
https://doi.org/10.1039/C3CC38471C
Article type
Communication
Submitted
25 Nov 2012
Accepted
17 Jan 2013
First published
29 Jan 2013

Chem. Commun., 2013,49, 1862-1864

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A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

T. Guo, L. Cui, J. Shen, R. Wang, W. Zhu, Y. Xu and X. Qian, Chem. Commun., 2013, 49, 1862 DOI: 10.1039/C3CC38471C

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