Issue 21, 2013

Metalated N-heterocyclic reagents prepared by the frustrated Lewis pair TMPMgCl·BF3 and their addition to aromatic aldehydes and activated ketones

Abstract

Treatment of pyridines, quinoline and methylthiopyrazine with the frustrated Lewis pair TMPMgCl·BF3 (1) leads to organotrifluoro borates which react readily with a variety of aromatic aldehydes in the absence of a transition metal catalyst.

Graphical abstract: Metalated N-heterocyclic reagents prepared by the frustrated Lewis pair TMPMgCl·BF3 and their addition to aromatic aldehydes and activated ketones

Supplementary files

Article information

Article type
Communication
Submitted
18 Dec 2012
Accepted
28 Jan 2013
First published
07 Feb 2013

Chem. Commun., 2013,49, 2124-2126

Metalated N-heterocyclic reagents prepared by the frustrated Lewis pair TMPMgCl·BF3 and their addition to aromatic aldehydes and activated ketones

S. M. Manolikakes, M. Jaric, K. Karaghiosoff and P. Knochel, Chem. Commun., 2013, 49, 2124 DOI: 10.1039/C3CC39040C

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