Issue 28, 2013
From the journal:

Chemical Communications

Folding single-stranded DNA to form the smallest 3D DNA triangular prism†

Xiaojin He,ab   Lei Dong,c   Wen Wang,a   Nian Lin*c  and  Yongli Mi*ab  

* Corresponding authors

a Department of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
E-mail: keymix@ust.hk
Fax: +852 23580054
Tel: +852 23587127

b Department of Chemistry, Tongji University, Shanghai, P. R. China 200092

c Department of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
E-mail: phnlin@ust.hk

Abstract

The smallest DNA 3D object, a triangular prism with only one turn on each edge, was constructed from a single-stranded DNA. We confirmed its structure using scanning tunneling microscopy. This work proves that single-stranded DNA can escape from kinetic traps to form stable topology.

Graphical abstract: Folding single-stranded DNA to form the smallest 3D DNA triangular prism

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Article information

DOI
https://doi.org/10.1039/C3CC39266J
Article type
Communication
Submitted
29 Dec 2012
Accepted
22 Feb 2013
First published
22 Feb 2013

Chem. Commun., 2013,49, 2906-2908

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Folding single-stranded DNA to form the smallest 3D DNA triangular prism

X. He, L. Dong, W. Wang, N. Lin and Y. Mi, Chem. Commun., 2013, 49, 2906 DOI: 10.1039/C3CC39266J

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