Issue 34, 2013
From the journal:

Chemical Communications

Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics†

Rajnikanth Sunke,a   Raju Adepu,a   Ravikumar Kapavarapu,b   Swetha Chintala,a   Chandana Lakshmi Teja Meda,a   Kishore V. L. Parsaa  and  Manojit Pal*a  

* Corresponding authors

a Dr Reddy's Institute of Life Sciences, University of Hyderabad Campus, Gachibowli, Hyderabad 500 046, India
E-mail: manojitpal@rediffmail.com
Tel: +91 40 6657 1500

b Doctoral Programme in Experimental Biology and Biomedicine, Center for Neuroscience and Cell Biology, University of Coimbra, 3004-517 Coimbra, Portugal

Abstract

A conceptually new and general strategy has been developed for the construction of a benzimidazole or a benzoxazole ring fused with isoquinolinone affording a diverse and unique class of small molecules as potential and novel inhibitors of PDE4.

Graphical abstract: Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics

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Article information

DOI
https://doi.org/10.1039/C3CC41337C
Article type
Communication
Submitted
22 Feb 2013
Accepted
11 Mar 2013
First published
13 Mar 2013

Chem. Commun., 2013,49, 3570-3572

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Vinylic amino group activation: a new and general strategy leading to functionalized fused heteroaromatics

R. Sunke, R. Adepu, R. Kapavarapu, S. Chintala, C. L. T. Meda, K. V. L. Parsa and M. Pal, Chem. Commun., 2013, 49, 3570 DOI: 10.1039/C3CC41337C

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