Preparation of magnetic rattle-type silica through a general and facile pre-shell–post-core process for simultaneous cancer imaging and therapy

Li Qiang; Xianwei Meng; Linlin Li; Dong Chen; Xiangling Ren; Huiyu Liu; Jun Ren; Changhui Fu; Tianlong Liu; Fuping Gao; Yanqi Zhang; Fangqiong Tang

doi:10.1039/C3CC43660H

Preparation of magnetic rattle-type silica through a general and facile pre-shell–post-core process for simultaneous cancer imaging and therapy†

Li Qiang,^ac Xianwei Meng,*^a Linlin Li,^a Dong Chen,*^b Xiangling Ren,^a Huiyu Liu,^a Jun Ren,^a Changhui Fu,^a Tianlong Liu,^a Fuping Gao,^a Yanqi Zhang^a and Fangqiong Tang*^a

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^a Laboratory of Controllable Preparation and Application of Nanomaterials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China
E-mail: tangfq@mail.ipc.ac.cn, mengxw@mail.ipc.ac.cn
Fax: +86-10-62554670
Tel: +86-10-82543521

^b Beijing Creative Nanophase Hi-Tech Company, Limited, Beijing 100086, People's Republic of China
E-mail: creative.nanophase@gmail.com

^c University of Chinese Academy of Sciences, Beijing 100049, People' Republic of China

Abstract

Here we report a novel pre-shell–post-core method for the fabrication of monodispersed magnetic rattle-type silica (MRS) through an entrapment process, which could be used as a promising theranostic agent for simultaneous magnetic resonance imaging and drug delivery.

Chemical Communications

Preparation of magnetic rattle-type silica through a general and facile pre-shell–post-core process for simultaneous cancer imaging and therapy†

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Preparation of magnetic rattle-type silica through a general and facile pre-shell–post-core process for simultaneous cancer imaging and therapy

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