Issue 71, 2013
From the journal:

Chemical Communications

Surface modification of mammalian cells with stimuli-responsive polymers†

Yasuhiko Iwasaki,*a   Mizuki Sakiyama,a   Shuetsu Fujiia  and  Shin-ichi Yusab  

* Corresponding authors

a 3-3-35 Yamate-cho, Suita-shi, Osaka 564-8680, Japan
E-mail: yasu.bmt@kansai-u.ac.jp
Fax: +81-6-6368-0090
Tel: +81-6-6368-0090

b 2167, Shosha, Himeji-shi, Hyogo 671-2280, Japan
E-mail: yusa@eng.u-hyogo.ac.jp
Fax: +81-792-66-8868
Tel: +81-792-67-4954

Abstract

In order to introduce alternative functions into mammalian cells and control them under ambient conditions, poly(N-isopropyl acrylamide) (PNIPAM) was immobilized on the cell surface. Cellular aggregation could be regulated by temperature change. In addition, separation of PNIPAM-conjugated glycoproteins was successfully performed.

Graphical abstract: Surface modification of mammalian cells with stimuli-responsive polymers

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Article information

DOI
https://doi.org/10.1039/C3CC44072A
Article type
Communication
Submitted
30 May 2013
Accepted
03 Jul 2013
First published
03 Jul 2013

Chem. Commun., 2013,49, 7824-7826

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Surface modification of mammalian cells with stimuli-responsive polymers

Y. Iwasaki, M. Sakiyama, S. Fujii and S. Yusa, Chem. Commun., 2013, 49, 7824 DOI: 10.1039/C3CC44072A

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