Issue 83, 2013
From the journal:

Chemical Communications

Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticle-assisted amplification†

Xu Hun,*ac   Wei Sun,*b   Huanhuan Zhu,a   Feng Du,a   Fang Liu,a   Yaqiong Xua  and  Yunhua Hed  

* Corresponding authors

a Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
E-mail: hunxu@sohu.com
Fax: +86-532-84023927
Tel: +86-532-84023927

b College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou 571158, China
E-mail: swyy26@hotmail.com
Fax: +86 898 31381637
Tel: +86 898 31381637

c State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, China

d School of Environmental Science and Engineering, Chang'an University, Xi'an 710054, China

Abstract

A new strategy for the electrochemical detection of thiols based on the disulfide cleavage combined with gold nanoparticle (AuNP) assisted signal amplification and an AuNP and graphene (GR) and ionic liquid (IL) modified carbon paste electrode (AuNP/GR/CILE). A superior detection limit of 0.4 pM toward glutathione could be achieved.

Graphical abstract: Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticle-assisted amplification

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Article information

DOI
https://doi.org/10.1039/C3CC44487B
Article type
Communication
Submitted
15 Jun 2013
Accepted
20 Aug 2013
First published
20 Aug 2013

Chem. Commun., 2013,49, 9603-9605

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Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticle-assisted amplification

X. Hun, W. Sun, H. Zhu, F. Du, F. Liu, Y. Xu and Y. He, Chem. Commun., 2013, 49, 9603 DOI: 10.1039/C3CC44487B

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