Issue 85, 2013
From the journal:

Chemical Communications

Systematic investigation of DNAs with modified cytosines under hot alkali treatment†

Tian Tian,‡a   Xiaoe Zhang,‡a   Boshi Fu,a   Yuelin Long,a   Shuang Peng,‡a   Shaoru Wang,*a   Xiang Zhou*ab  and  Xin Zhouc  

* Corresponding authors

a College of Chemistry and Molecular Sciences, Key Laboratory of Biomedical Polymers of Ministry of Education, State Key Laboratory of Virology, Wuhan University, Wuhan, Hubei, P. R. China
E-mail: xzhou@whu.edu.cn, srwang@whu.edu.cn
Fax: +86-27-68756663
Tel: +86-27-68756663

b State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing, China

c Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China

Abstract

We have conducted the first systematic investigation of DNAs with modified cytosines, including 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), under hot alkali treatment.

Graphical abstract: Systematic investigation of DNAs with modified cytosines under hot alkali treatment

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Article information

DOI
https://doi.org/10.1039/C3CC45423A
Article type
Communication
Submitted
18 Jul 2013
Accepted
19 Aug 2013
First published
20 Aug 2013

Chem. Commun., 2013,49, 9968-9970

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Systematic investigation of DNAs with modified cytosines under hot alkali treatment

T. Tian, X. Zhang, B. Fu, Y. Long, S. Peng, S. Wang, X. Zhou and X. Zhou, Chem. Commun., 2013, 49, 9968 DOI: 10.1039/C3CC45423A

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