Issue 83, 2013
From the journal:

Chemical Communications

Improved solubility of DNA in recyclable and reusable bio-based deep eutectic solvents with long-term structural and chemical stability†

Dibyendu Mondal,a   Mukesh Sharma,a   Chandrakant Mukesh,a   Vishal Guptaa  and  Kamalesh Prasad*ab  

* Corresponding authors

a AcSIR-Central Salt & Marine Chemicals Research Institute, G. B. Marg, Bhavnagar-364002, Gujarat, India

b Marine Biotechnology and Ecology Discipline, CSIR-Central Salt & Marine Chemicals Research Institute, G. B. Marg, Bhavnagar-364002, Gujarat, India
E-mail: kamlesh@csmcri.org, drkamaleshp@gmail.com
Fax: +91-278-2567562
Tel: +91-278-2567760

Abstract

The solubility of DNA in bio-based deep eutectic solvents (DESs) consisting of mixtures of choline chloride with levulinic acid, glycerol, ethylene glycol, sorbitol and resorcinol was investigated. The macromolecule was found to be soluble and chemically and structurally stable in DESs consisting of mixtures containing glycerol and ethylene glycol. Furthermore recyclability of the DESs was demonstrated over three consecutive reuses in DNA dissolution.

Graphical abstract: Improved solubility of DNA in recyclable and reusable bio-based deep eutectic solvents with long-term structural and chemical stability

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Article information

DOI
https://doi.org/10.1039/C3CC45849K
Article type
Communication
Submitted
31 Jul 2013
Accepted
21 Aug 2013
First published
22 Aug 2013

Chem. Commun., 2013,49, 9606-9608

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Improved solubility of DNA in recyclable and reusable bio-based deep eutectic solvents with long-term structural and chemical stability

D. Mondal, M. Sharma, C. Mukesh, V. Gupta and K. Prasad, Chem. Commun., 2013, 49, 9606 DOI: 10.1039/C3CC45849K

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