Issue 84, 2013

Facile and efficient KOH-catalysed reduction of esters and tertiary amides

Abstract

Esters and tertiary amides were efficiently reduced to their corresponding alcohols and amines in high yields under mild and environmentally friendly conditions. The presented KOH-catalysed system involves a simple hydrosilylation procedure that is carried out under solvent-free conditions and does not require the use of inert conditions.

Graphical abstract: Facile and efficient KOH-catalysed reduction of esters and tertiary amides

Supplementary files

Article information

Article type
Communication
Submitted
02 Aug 2013
Accepted
28 Aug 2013
First published
03 Sep 2013

Chem. Commun., 2013,49, 9758-9760

Facile and efficient KOH-catalysed reduction of esters and tertiary amides

J. A. Fernández-Salas, S. Manzini and S. P. Nolan, Chem. Commun., 2013, 49, 9758 DOI: 10.1039/C3CC45930F

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