Issue 90, 2013
From the journal:

Chemical Communications

A near-infrared dye based on BODIPY for tracking morphology changes in mitochondria†

Na Jiang,a   Jiangli Fan,*a   Tao Liu,a   Jianfang Cao,a   Bo Qiao,a   Jingyun Wang,b   Pan Gaob  and  Xiaojun Peng*a  

* Corresponding authors

a State Key Laboratory of Fine Chemicals, Dalian University of Technology, No. 2 Linggong Road, High-Tech District, Dalian 116024, China
E-mail: fanjl@dlut.edu.cn, pengxj@dlut.edu.cn
Fax: +86 411 84986306
Tel: +86 411 84986327

b School of Life Science and Biotechnology, Dalian University of Technology, Dalian, China

Abstract

M-DPT, a BODIPY-based water soluble near-infrared fluorescent probe with thiophene at the 1,7-position, is synthesized. M-DPT is found to possess high specificity to mitochondria, superior photostability, and appreciable tolerance to microenvironmental changes. Thus, this probe is a highly suitable imaging agent for targeting mitochondria and tracking morphology changes.

Graphical abstract: A near-infrared dye based on BODIPY for tracking morphology changes in mitochondria

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Article information

DOI
https://doi.org/10.1039/C3CC46143B
Article type
Communication
Submitted
12 Aug 2013
Accepted
23 Sep 2013
First published
24 Sep 2013

Chem. Commun., 2013,49, 10620-10622

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A near-infrared dye based on BODIPY for tracking morphology changes in mitochondria

N. Jiang, J. Fan, T. Liu, J. Cao, B. Qiao, J. Wang, P. Gao and X. Peng, Chem. Commun., 2013, 49, 10620 DOI: 10.1039/C3CC46143B

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