Issue 6, 2013
From the journal:

RSC Advances

A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase†

Ka-Ho Leung,a   Hong-Zhang He,a   Victor Pui-Yan Ma,a   Hui Yang,a   Daniel Shiu-Hin Chan,a   Chung-Hang Leung*b  and  Dik-Lung Ma*a  

* Corresponding authors

a Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China
E-mail: edmondma@hkbu.edu.hk

b State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China
E-mail: DuncanLeung@umac.mo

Abstract

A novel G-quadruplex-selective luminescent iridium(III) complex has been employed as a signal-transducing element for the sensitive and selective switch-on detection of sub-nanomolar human neutrophil elastase (HNE) in homogenous solution.

Graphical abstract: A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase

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Article information

DOI
https://doi.org/10.1039/C2RA21996D
Article type
Communication
Submitted
30 Aug 2012
Accepted
14 Nov 2012
First published
14 Nov 2012

RSC Adv., 2013,3, 1656-1659

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A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase

K. Leung, H. He, V. P. Ma, H. Yang, D. S. Chan, C. Leung and D. Ma, RSC Adv., 2013, 3, 1656 DOI: 10.1039/C2RA21996D

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