A sensitive voltammetric sensor for salbutamol based on MWNTs composite nano-Au film modified electrode

Abstract

A novel voltammetric sensor for salbutamol is fabricated via self-assembly of gold nanoparticles on multi-walled carbon nanotubes and Nafion modified electrode. This sensor could improve the oxidation of salbutamol intensively. The oxidation process of salbutamol is studied and some dynamic parameters are calculated using various electrochemical techniques. Under the optimum conditions, the response peak currents have a linear relationship with the salbutamol concentrations in the range of 9.0 × 10⁻⁸ to 7.0 × 10⁻⁶ mol L⁻¹ with a detectable limit of 5.0 × 10⁻⁸ mol L⁻¹. The proposed method is successfully applied to the determination of salbutamol in commercial pharmaceuticals and human serum samples with good accuracy and satisfactory recovery.