Abstract
An efficient method for the synthesis of amides via Pd-catalyzed oxidative carbonylation of C(sp3)–H bonds with CO and amines is described. The route efficiently provides substituted phenyl amides from alkanes.
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* Corresponding authors
a
Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland
E-mail:
Paul.Dyson@epfl.ch
Fax: +41-21-6939865
An efficient method for the synthesis of amides via Pd-catalyzed oxidative carbonylation of C(sp3)–H bonds with CO and amines is described. The route efficiently provides substituted phenyl amides from alkanes.
H. Liu, G. Laurenczy, N. Yan and P. J. Dyson, Chem. Commun., 2014, 50, 341 DOI: 10.1039/C3CC47015F
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