A facile mechanophore functionalization of an amphiphilic block copolymer towards remote ultrasound and redox dual stimulus responsiveness†
Abstract
Two different site-specific cleavage mechanisms for copolymer micelles under ultrasound and redox were confirmed. The finding that ultrasound induced mechanochemical cleavage of central ester bonds can open up a new way in the design of novel ultrasound responsive copolymer micelles for drug release.