Issue 27, 2014

A facile mechanophore functionalization of an amphiphilic block copolymer towards remote ultrasound and redox dual stimulus responsiveness

Abstract

Two different site-specific cleavage mechanisms for copolymer micelles under ultrasound and redox were confirmed. The finding that ultrasound induced mechanochemical cleavage of central ester bonds can open up a new way in the design of novel ultrasound responsive copolymer micelles for drug release.

Graphical abstract: A facile mechanophore functionalization of an amphiphilic block copolymer towards remote ultrasound and redox dual stimulus responsiveness

Supplementary files

Article information

Article type
Communication
Submitted
06 Jan 2014
Accepted
10 Feb 2014
First published
11 Feb 2014

Chem. Commun., 2014,50, 3575-3578

A facile mechanophore functionalization of an amphiphilic block copolymer towards remote ultrasound and redox dual stimulus responsiveness

R. Tong, X. Lu and H. Xia, Chem. Commun., 2014, 50, 3575 DOI: 10.1039/C4CC00103F

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