Issue 46, 2014
From the journal:

Chemical Communications

Four-component strategy for selective synthesis of azepino[5,4,3-cd]indoles and pyrazolo[3,4-b]pyridines†

Bo Jiang,*a   Qin Ye,a   Wei Fan,a   Shu-Liang Wang,a   Shu-Jiang Tu*a  and  Guigen Libc  

* Corresponding authors

a Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, Jiangsu Normal University, Xuzhou, P. R. China
E-mail: jiangchem@jsnu.edu.cn, laotu@jsnu.edu.cn
Fax: +86 51683500065
Tel: +86 51683500065

b Institute of Chemistry & Biomedical Sciences, Nanjing University, Nanjing 210093, P. R. China

c Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409-1061, USA
E-mail: guigen.li@ttu.edu

Abstract

A novel four-component strategy for the selective synthesis of fused azepino[5,4,3-cd]indoles and pyrazolo [3,4-b]pyridines has been established. The bond-forming efficiency, accessibility of starting materials and substrate scope provide invaluable access to tetra-, and bis-heterocyclic scaffolds.

Graphical abstract: Four-component strategy for selective synthesis of azepino[5,4,3-cd]indoles and pyrazolo[3,4-b]pyridines

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Article information

DOI
https://doi.org/10.1039/C4CC00740A
Article type
Communication
Submitted
28 Jan 2014
Accepted
04 Mar 2014
First published
12 Mar 2014

Chem. Commun., 2014,50, 6108-6111

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Four-component strategy for selective synthesis of azepino[5,4,3-cd]indoles and pyrazolo[3,4-b]pyridines

B. Jiang, Q. Ye, W. Fan, S. Wang, S. Tu and G. Li, Chem. Commun., 2014, 50, 6108 DOI: 10.1039/C4CC00740A

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