Ligand tuning of single-site manganese-based catalytic antioxidants with dual superoxide dismutase and catalase activity

Abstract

A bio-inspired manganese(II) complex with a linear pentadentate ligand framework containing soft sulfur donors and an alternating NSNSN binding motif displays excellent dual CAT/SOD-like antioxidant activity with high turnover efficiency and good operation stability in an aqueous environment.