Issue 29, 2014

Kinetic control in the CID-induced elimination of H3PO4 from phosphorylated serine probed using IRMPD spectroscopy

Abstract

InfraRed Multiple Photon Dissociation (IRMPD) spectroscopy was used to assay the structural features of the fragment ions resulting from the elimination of H3PO4 in the Collision-Induced Dissociation (CID) of protonated serine. The results are interpreted with the aid of density functional theory calculations. Experiment and theory point to an aziridine-ring structure, implying participation of the vicinal amino group in the formation of this species. This finding constitutes a benchmark for investigating the same process in the CID of phosphorylated peptides.

Graphical abstract: Kinetic control in the CID-induced elimination of H3PO4 from phosphorylated serine probed using IRMPD spectroscopy

Supplementary files

Article information

Article type
Communication
Submitted
02 Feb 2014
Accepted
21 Feb 2014
First published
24 Feb 2014

Chem. Commun., 2014,50, 3845-3848

Author version available

Kinetic control in the CID-induced elimination of H3PO4 from phosphorylated serine probed using IRMPD spectroscopy

F. Lanucara, B. Chiavarino, D. Scuderi, P. Maitre, S. Fornarini and M. E. Crestoni, Chem. Commun., 2014, 50, 3845 DOI: 10.1039/C4CC00877D

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