A simple, toehold-mediated two-way input DNA machine has been developed. Utilizing symmetric and asymmetric protector sequences, INH, XOR logic gates and a half-subtractor are designed based on this two-way structure.
Y. Liu, B. Dong, Z. Wu, W. Fang, G. Zhou, A. Shen, X. Zhou and J. Hu, Chem. Commun., 2014, 50, 12026 DOI: 10.1039/C4CC01883D
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