Issue 63, 2014
From the journal:

Chemical Communications

Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging†

Ji-Ting Hou,a   Ming-Yu Wu,a   Kun Li,*ab   Jin Yang,a   Kang-Kang Yu,a   Yong-Mei Xie*b  and  Xiao-Qi Yu*a  

* Corresponding authors

a Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu, P. R. China
E-mail: kli@scu.edu.cn, xqyu@scu.edu.cn
Fax: +86-28-85415886

b State Key Laboratory of Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China
E-mail: xieym@scu.edu.cn

Abstract

Two mitochondria-targeted real-time probes were presented, which could selectively respond to hypochlorite over other ROS. Meanwhile, the “off–on” probes could be successfully applied in the in vivo imaging of hypochlorite in living mice.

Graphical abstract: Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging

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Article information

DOI
https://doi.org/10.1039/C4CC02673J
Article type
Communication
Submitted
11 Apr 2014
Accepted
15 May 2014
First published
15 May 2014

Chem. Commun., 2014,50, 8640-8643

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Mitochondria-targeted colorimetric and fluorescent probes for hypochlorite and their applications for in vivo imaging

J. Hou, M. Wu, K. Li, J. Yang, K. Yu, Y. Xie and X. Yu, Chem. Commun., 2014, 50, 8640 DOI: 10.1039/C4CC02673J

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