Issue 65, 2014
From the journal:

Chemical Communications

DNA gated photochromism and fluorescent switch in a thiazole orange modified diarylethene†

Keyin Liu,a   Ying Wen,a   Ting Shi,b   Yi Li,a   Fuyou Li,a   Yi-lei Zhao,b   Chunhui Huanga  and  Tao Yi*a  

* Corresponding authors

a Department of Chemistry, and Concerted Innovation Center of Chemistry for Energy Materials, Fudan University, 220 Handan Road, Shanghai 200433, P. R. China
E-mail: yitao@fudan.edu.cn

b State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, P. R. China

Abstract

Thiazole orange-modified diarylethene (1) shows weak fluorescence but no photochromism in aqueous solution. When binding with DNA, the fluorescence of 1 is enhanced drastically and the photochromic reactivity is unlocked. This kind of DNA-responsive photoswitchable system can be used for imaging nucleic acids within cells.

Graphical abstract: DNA gated photochromism and fluorescent switch in a thiazole orange modified diarylethene

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Article information

DOI
https://doi.org/10.1039/C4CC02783C
Article type
Communication
Submitted
15 Apr 2014
Accepted
23 Jun 2014
First published
24 Jun 2014

Chem. Commun., 2014,50, 9141-9144

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DNA gated photochromism and fluorescent switch in a thiazole orange modified diarylethene

K. Liu, Y. Wen, T. Shi, Y. Li, F. Li, Y. Zhao, C. Huang and T. Yi, Chem. Commun., 2014, 50, 9141 DOI: 10.1039/C4CC02783C

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