Herein, we present a fluorescent-peptide drug delivery system composed of biotin–naphthalimide–HJ inhibitor peptide2, prodrug 1. Treatment of 1 to biotin receptor-positive HepG2 cells, which are resistant to high concentrations of the HJ inhibitor peptide2, decreased cell viability and increased intracellular fluorescence.
T. Kim, H. M. Jeon, H. T. Le, T. W. Kim, C. Kang and J. S. Kim, Chem. Commun., 2014, 50, 7690 DOI: 10.1039/C4CC02878C
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