Homogeneous Pd-catalyzed asymmetric hydrogenation of 3-phthalimido substituted quinolines was successfully developed, providing facile access to chiral substituted tetrahydroquinolines bearing two contiguous stereogenic centers with up to 90% ee.
X. Cai, W. Huang, Z. Chen and Y. Zhou, Chem. Commun., 2014, 50, 9588 DOI: 10.1039/C4CC04386C
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